35) Preprint
Daniel R. Goodwin, Alex Vaughan, Daniel Leible, Shahar Alon, Gilbert L. Henry, Anne Cheng, Xiaoyin Chen, Ruihan Zhang, Andrew G. Xue, Asmamaw T. Wassie, Anubhav Sinha, Yosuke Bando, Atsushi Kajita, Adam H. Marblestone, Anthony M. Zador, Edward S. Boyden, George M. Church, Richie E. Kohman. “Expansion Sequencing of RNA Barcoded Neurons in the Mammalian Brain: Progress and Implications for Molecularly Annotated Connectomics”
Link
34) Preprint
Christian Kramme, Merrrick Pierson Smela, Bennett Wolf, Patrick R Fortuna, Garyk Brixi, Kalyan Palepu, Edward Dong, Jessica L Adams, Suhaas Bhat, Sabrina Koseki, Emma Tysinger, Teodora Stan, Richie E Kohman, Songlei Liu, Mutsumi Kobayashi, Toshi Shioda, George M Church, Pranam Chatterjee. “Efficient Human Germ Cell Specification from Stem Cells via Combinatorial Expression of Transcription Factors”
Link
33) Preprint
Merrick Pierson Smela, Christian Kramme, Patrick Fortuna, Jessica Adams, Edward Dong, Mutsumi Kobayashi, Garyk Brixi, Emma Tysinger, Richie. E. Kohman, Toshi Shioda, Pranam Chatterjee, George M. Church. “Directed Differentiation of Human iPSCs to Functional Ovarian Granulosa-Like Cells via Transcription Factor Overexpression”
Link
Daniel R. Goodwin, Alex Vaughan, Daniel Leible, Shahar Alon, Gilbert L. Henry, Anne Cheng, Xiaoyin Chen, Ruihan Zhang, Andrew G. Xue, Asmamaw T. Wassie, Anubhav Sinha, Yosuke Bando, Atsushi Kajita, Adam H. Marblestone, Anthony M. Zador, Edward S. Boyden, George M. Church, Richie E. Kohman. “Expansion Sequencing of RNA Barcoded Neurons in the Mammalian Brain: Progress and Implications for Molecularly Annotated Connectomics”
bioRxiv, 2022, 2022.07.31.502046.
Link
34) Preprint
Christian Kramme, Merrrick Pierson Smela, Bennett Wolf, Patrick R Fortuna, Garyk Brixi, Kalyan Palepu, Edward Dong, Jessica L Adams, Suhaas Bhat, Sabrina Koseki, Emma Tysinger, Teodora Stan, Richie E Kohman, Songlei Liu, Mutsumi Kobayashi, Toshi Shioda, George M Church, Pranam Chatterjee. “Efficient Human Germ Cell Specification from Stem Cells via Combinatorial Expression of Transcription Factors”
bioRxiv, 2022, 2022.07.11.499564.
Link
33) Preprint
Merrick Pierson Smela, Christian Kramme, Patrick Fortuna, Jessica Adams, Edward Dong, Mutsumi Kobayashi, Garyk Brixi, Emma Tysinger, Richie. E. Kohman, Toshi Shioda, Pranam Chatterjee, George M. Church. “Directed Differentiation of Human iPSCs to Functional Ovarian Granulosa-Like Cells via Transcription Factor Overexpression”
bioRxiv, 2022, 2022.07.04.498717.
Link
32) Article
Mutsumi Kobayashi, Misato Kobayashi, Junko Odajima, Keiko Shioda, Young Sun Hwang, Kotaro Sasaki, Pranam Chatterjee, Christian Kramme, Richie E Kohman, George M Church, Amanda R Loehr, Robert S Weiss, Harald Jüppner, Joanna J Gell, Ching C Lau, Toshi Shioda. “Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers” Stem Cell Reports, 2022, 17, 507-521.
Link
31) Article
Christian Kramme, Alexandru M Plesa, Helen H Wang, Bennett Wolf, Merrick Pierson Smela, Xiaoge Guo, Richie E Kohman, Pranam Chatterjee, George M Church. “An integrated pipeline for mammalian genetic screening” Cell Reports Methods, STAR Protocols, 2021, 2, 100907.
Link
30) Article
Christian Kramme, Alexandru M Plesa, Helen H Wang, Bennett Wolf, Merrick Pierson Smela, Xiaoge Guo, Richie E Kohman, Pranam Chatterjee, George M Church. “An integrated pipeline for mammalian genetic screening” Cell Reports Methods, 2021, 1, 100082.
Link
29) Article
Tal Gilboa, Limor Cohen, Chi-An Cheng, Roey Lazarovits, Augusta Uwamanzu-Nna, Isaac Han, Kettner Griswold, Nick Barry, David B Thompson, Richie E Kohman, Ann E Woolley, Elizabeth W Karlson, David Walt. “A SARS‐CoV‐2 Neutralization Assay using Single Molecule Arrays“ Angew. Chem. Int. Ed. Angew. Chem. Int. Ed. 2021, 60(49), 25966-25972.
Link
28) Article
Songlei Liu, Sukanya Punthambaker, Eswar P R Iyer, Thomas Ferrante, Daniel Goodwin, Daniel Fürth, Andrew C Pawlowski, Kunal Jindal, Jenny M Tam, Lauren Mifflin, Shahar Alon, Anubhav Sinha, Asmamaw T Wassie, Fei Chen, Anne Cheng, Valerie Willocq, Katharina Meyer, King-Hwa Ling, Conor K Camplisson, Richie E Kohman, John Aach, Je Hyuk Lee, Bruce A Yankner, Edward S Boyden, George M Church. “Barcoded Oligonucleotides Ligated on RNA Amplified for Multiplex and Parallel in-situ Analyses” Nucleic Acids Research, gkab120, https://doi.org/10.1093/nar/gkab120Link
27) Article
Shahar Alon, Daniel R. Goodwin, Anubhav Sinha, Asmamaw T. Wassie, Fei Chen, Evan R. Daugharthy, Yosuke Bando, Atsushi Kajita, Andrew G. Xue, Karl Marrett, Robert Prior, Yi Cui, Andrew C. Payne, Chun-Chen Yao, Ho-Jun Suk, Ru Wang, Chih-Chieh (Jay) Yu, Paul Tillberg, Paul Reginato, Nikita Pak, Songlei Liu, Sukanya Punthambaker, Eswar P. R. Iyer, Richie E. Kohman, Jeremy A. Miller, Ed S. Lein, Ana Lako, Nicole Cullen, Scott Rodig, Karla Helvie, Daniel L. Abravanel, Nikhil Wagle, Bruce E. Johnson, Johanna Klughammer, Michal Slyper, Julia Waldman, Judit Jané-Valbuena, Orit Rozenblatt-Rosen, Aviv Regev, IMAXT Consortium, George M. Church, Adam H. Marblestone, Edward S. Boyden “ Expansion Sequencing: Spatially Precise in situ Transcriptomics in Intact Biological Systems ” Science, 2021, Vol. 371, Issue 6528, eaax2656 DOI: 10.1126/science.aax2656.
Link
26) Article
Alex H. M. Ng, Parastoo Khoshakhlagh, Jesus Eduardo Rojo Arias, Giovanni Pasquini, Kai Wang, Anka Swiersy, Seth L. Shipman, Evan Appleton, Kiavash Kiaee, Richie E. Kohman, Andyna Vernet, Matthew Dysart, Kathleen Leeper, Wren Saylor, Jeremy Y. Huang, Amanda Graveline, Jussi Taipale, David E. Hill, Marc Vidal, Juan M. Melero-Martin, Volker Busskamp, George M. Church “A Comprehensive Library of Human Transcription Factors for Cell Fate Engineering“ Nature Biotechnology, 2020, https://doi.org/10.1038/s41587-020-0742-6.
Link
Brian M Turczyk, Michele Busby, Allison L Martin, Evan R Daugharthy, Daniel Myung, Richard C Terry, Samuel A Inverso, Richie E Kohman, George M Church “Spatial Sequencing: A Perspective” Journal of Biomolecular Techniques, 2020, Jul; 31(2): 44–46.
Link
24) Preprint
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Richie E Kohman*, George M Church* “Fluorescent in situ sequencing of DNA barcoded antibodies” bioRxiv, 2020, 2020.04.27.060624.
*co-correscponding authors
Link
Richie E Kohman*, George M Church* “Fluorescent in situ sequencing of DNA barcoded antibodies” bioRxiv, 2020, 2020.04.27.060624.
*co-correscponding authors
Link
23) Article
Howon Lee, Daniel J. Wiegand, Kettner Griswold, Sukanya Punthambaker, Honggu Chun, Richie E. Kohman*, George M. Church* “ Photon-directed Multiplexed Enzymatic DNA Synthesis for Molecular Digital Data Storage” Nature Communications, 2020, 11, 5246. https://doi.org/10.1038/s41467-020-18681-5.
*co-correscponding authors
Link
22) Patent
Kettner John Frederick Griswold Jr., Richie E. Kohman, George M. Church, Jonathan Rittichier “Cleavable Nucleotide Analogs and Uses Thereof ” US20200080122A1, 2020.
Link
21) Preprint
Yu Wang, Yitian Zeng, Sinem K. Saka, Wenxin Xie, Isabel Goldaracena, Richie E. Kohman, Peng
Yin, George M. Church. “Multiplexed in situ protein imaging using DNA barcoded antibodies with extended hybridization chain reactions” bioRxiv, 2020, 274456v3.
Link
20) Patent
Richie E. Kohman and George M. Church “Targeted expansion fluorescent in situ sequencing ” WO2018226930A1, 2018.
Link
19) Review
Richie E Kohman, Aditya M Kunjapur, Eriona Hysolli, Yu Wang, George M Church. “From Designing the Molecules of Life to Designing Life: Future Applications Derived from Advances in DNA Technologies” Angew. Chem. Int. Ed. 2018, 57, 4313-4328.Link
18) Patent
Richie E. Kohman “Combining Modified Antibodies with Expansion Microscopy for in-situ, Spatially-resolved Proteomics” US Patent App. 15/592,221, 2018.
Link
17) Patent
Xue Han, Richie E. Kohman, Susue Cha “Light-stimulated release of cargo from oligonucleotides” WO2017151748A1, 2017.
Link
16) Patent
Richie E. Kohman “Combining Protein Barcoding with Expansion Microscopy for in-situ, Spatially-resolved Proteomics” US Patent App. 15/446,005, 2017.
Link
15) Article
Richie E. Kohman, Susie S. Cha, Heng-Ye Man, and Xue Han. “Light-Triggered Release of Bioactive Cargo from DNA Nanocages.” Nano. Letters 2016, 16, 2781–2785.
Link
Highlighted in Boston University
Link
Highlighted in ReliaWire
Link
14) Article
Benjamin S. Bleier*, Richie E Kohman*, Kevin Guerra, Angela L. Nocera, Armine H. Kocharyan, Shreshtha Ramanlal, and Xue Han. “Heterotopic Mucosal Grafting Enables the Delivery of Therapeutic Neuropeptides Across the Blood Brain Barrier.” Neurosurgery 2016, 78, 448-457.
*co-first authors Link
Highlighted in NeuroscienceNews
Link
Highlighted in KurzweilAI
Link
Highlighted in Parkinson's News Today
Link
13) Article
Richie E. Kohman, and Xue Han. "Light-Sensitization of DNA Nanostructures via Incorporation of Photo-Cleavable Spacers." Chem. Commun. 2015, 51, 5747-5750. Link
12) Book Chapter
Hua-an Tseng, Richie E. Kohman, and Xue Han. “Chapter 9: Optogenetics and Electrophysiology” Basic Electrophysiological Methods. Oxford University Press. 2015. Link
11) Article
Richie E. Kohman, Xue Han, and Benjamin S. Bleier. “Heterotopic Mucosal Engrafting Procedure for Direct Drug Delivery to the Brain in Mice.” J. Vis. Exp. 2014. Link
10) Book Chapter
Richie E. Kohman, Hua-an Tseng, and Xue Han. “Chapter 14 Optogenetics” The OMICs: Applications in Neuroscience. Oxford University Press. 2014.
Link
9) Article
John J. Schmidt*, Jae Hyun Jeong*, Richie E. Kohman*, Andrew Zill, Ross DeVolder, Artem
Shkumatov, Lawrence Schook, Steven C. Zimmerman, and Hyunjoon Kong. “Leukocyte-Mimicking Stem Cell Delivery via in situ Coating of Cells with a Bioactive Hyperbranched Polyglycerol.” J. Am. Chem. Soc. 2013, 135, 8770-8773.
*co-first authors Link
Highlighted as J. Am. Chem. Soc. cover June 19, 2013, Volume 135, Number 24
Link
Highlighted in “Spotlight on Recent JACS Publications” in J. Am. Chem. Soc.
J. Am. Chem. Soc., 2013, 135, 8763.
Link
Highlighted in “Editor’s Choice” in Science
Science, 2013, 340, 389.
Highlighted in Chem. Eng. News: “Putting Step Cells In Their Place” April 25, 2013
Link
8) Article
Benjamin S. Bleier, Richie E. Kohman, Rachel Feldman, Shreshtha Ramanlal, and Xue Han.
“Permeabilization of the Blood-Brain Barrier via Mucosal Engrafting: Implications for Drug Delivery
to the Brain.” PLOS ONE 2013, 8, e61694.
Link
Highlighted in ScienceDaily
Link
Highlighted in KirzweilAI
Link
7) Article
Xiao-Xiang Zhang, Caroline M. LaManna, Richie E. Kohman, Thomas J. McIntosh, Xue Han, and
Mark W. Grinstaff. “Lipid mediated DNA and siRNA Transfection Efficiency Depends on Peptide
Headgroup.” Soft Matter 2013, 9, 4472-4479.
Link
6) Article
Youyun Liang, Tor W. Jensen, Edward J. Roy, Chaenyung Cha, Ross J. DeVolder, Richie E. Kohman, Bao Zhong Zhang, Kyle B. Textor, Lauretta A. Rund, Lawrence B. Schook, Yen Wah Tong, and Hyunjoon Kong. “Tuning the Non-equilibrium State of a Drug-encapsulated Poly(ethylene glycol) Hydrogel for Stem and Progenitor Cell Mobilization.” Biomaterials 2011, 32, 2004-2012. Link
5) Article
Andrew Zill, Alexandra Rutz, Richie E. Kohman, Alaaldin M. Alkilany, Catherine J. Murphy, Hyunjoon Kong, and Steven C. Zimmerman. “Clickable Polyglycerol Hyperbranched Polymers and Their Application to Gold Nanoparticles and Acid-Labile Nanocarriers.” Chem. Commun. 2011, 47, 1279-1281. Link
4) Article
Richie E. Kohman, Chaenyung Cha, Steven C. Zimmerman, and Hyunjoon Kong. “Tuning Hydrogel Properties and Function Using Substituent Effects.” Soft Mater 2010, 6, 2150-2152. Link
3) Article
Chaenyung Cha, Richie E. Kohman, and Hyunjoon Kong. “Biodegradable Polymer Cross-linker: Independent Control of Stiffness, Toughness and Hydrogel Degradation Rate.” Adv. Funct. Mater. 2009, 19, 3056-3062. Link
2) Article
Richie E. Kohman, and Steven C. Zimmerman. “Degradable Dendrimers Divergently Synthesized via Click Chemistry.” Chem. Commun. 2009, 794-796. Link
1) Article
Amy M. Balija, Richie E. Kohman, and Steven C. Zimmerman. Substituted 1,3,5-Triazaadamantanes: Biocompatible and Degradable Building Blocks.” Angew. Chem. Int. Ed. 2008, 47, 8072-8084. Link