Richie E. Kohman, Ph.D

I am a senior research scientist and the Lead of the Synthetic Biology Platorm at the Wyss Institute for Biologically Inspired Engineering at Harvard University.  I oversee all research conducted by the Synthetic Biology Platform including advances in nucleic acid synthesis, in situ sequencing, gene editing, genome recoding, gene therapy, stem cell therapy, extinct species resurrection, and all aspects relating to the intersection of synthetic biology and synthetic chemistry.  I am also co-PI, along with George Church at the Department of Genetic at Harvard Medical School, of an IARPA-funded project to map synaptic connectivity in large brain volumes.

I have spent much of my career working at the interface of chemistry and biology, with an emphasis on neurotechnology and gene/drug delivery. Prior to joining the Wyss, I worked as a Group Leader at Expansion Technologies, Inc. where I brought to market techniques and reagents for high resolution molecular mapping of tissues. As a postdoctoral fellow in the Department of Biomedical Engineering at Boston University and an affiliate of the MIT Media Lab, I developed surgical methods to deliver large molecules to the brain and created neurotransmitter-releasing DNA nanostructures.  Prior to moving to Boston, I obtained my PhD in Organic Chemistry at the University of Illinois Urbana-Champaign where I synthesized novel, degradable materials to interface with cells and tissues.

This website has information about recent and past research projects as well as my background and publication history. Additional profiles can be found at Google Scholar, LinkedIn, and ResearchGate.
Mark